Gene information
Official symbol ITGA2B
Official full name integrin subunit alpha 2b
Gene type protein-coding gene
Chromosome17q21.31
Alias symbolCD41B; CD41; PPP1R93
Previous symbolGP2B
Gene familyCD molecules; Protein phosphatase 1 regulatory subunits; Integrin alpha subunits
Resources
Entrez Gene 3674
HGNC HGNC:6138
Ensembl ENSG00000005961
Vega OTTHUMG00000177935
UCSC uc002igt.2
GO terms: 21 records
GO Description Category LogP Number of genes Detail
GO:0001525 angiogenesis GO Biological Processes -32.8794581 74 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0007229 integrin-mediated signaling pathway GO Biological Processes -5.80936917 16 More
GO:0008305 integrin complex GO Cellular Components -2.23601792 3 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031092 platelet alpha granule membrane GO Cellular Components -5.90191637 5 More
GO:0031589 cell-substrate adhesion GO Biological Processes -10.7590108 32 More
GO:0033627 cell adhesion mediated by integrin GO Biological Processes -3.57905448 8 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0050839 cell adhesion molecule binding GO Molecular Functions -14.4506551 68 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098636 protein complex involved in cell adhesion GO Cellular Components -5.90313372 12 More
GO:0098797 plasma membrane protein complex GO Cellular Components -14.6387951 39 More
GO:0098802 plasma membrane signaling receptor complex GO Cellular Components -6.47096721 17 More
KEGG pathways: 10 records
KEGG Description Category LogP Number of genes Detail
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04510 Focal adhesion KEGG Pathway -16.5268196 41 More
hsa04512 ECM-receptor interaction KEGG Pathway -16.8587083 28 More
hsa04611 Platelet activation KEGG Pathway -14.0379587 18 More
hsa04613 Neutrophil extracellular trap formation KEGG Pathway -12.8071279 20 More
hsa05165 Human papillomavirus infection KEGG Pathway -8.63301470 40 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05222 Small cell lung cancer KEGG Pathway -6.83164026 10 More
hsa05412 Arrhythmogenic right ventricular cardiomyopathy KEGG Pathway -1.87478399 4 More
hsa05414 Dilated cardiomyopathy KEGG Pathway -7.04373804 18 More
Drug-Gene interaction
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Related drugs: 9 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_000419.5:c.2621T>G genomics acute myocardial infarction[diagnosis] acute myocardial infarction Reiner AP et al. Br J Haematol. 2001
NM_000419.5:c.2621T>G genomics myocardial infarction[diagnosis] myocardial infarction Park S et al. Yonsei Med J. 2004
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